PrenaTest® is a molecular genetic method that is able to examine the cell-free fetal DNA fragments circulating in the mother’s blood, determine their origin (that is, which chromosome they come from) and quantity. For instance, a fetus with Down syndrome (trisomy 21) sheds cell-free DNA with an extra 21st chromosome into the mother’s blood, which can be very effectively screened for using this new method.
Using PrenaTest® , trisomies 21, 18, and 13 (Down-, Edwards- and Patau syndromes) can be detected, as can sex chromosome abnormalities (Turner-, Klinefelter-, Jakob-, Triple X syndromes).
The effectiveness of this risk-free maternal blood test was determined by international clinical studies with a large number of patients. The molecular genetic testing method based on the new generation sequencing technology is close to 100% effective, based on the results of several clinical trials.
When PrenaTest® is performed:
The test can be performed at any time between the 9th (9+0) and 20th (19+6) week of pregnancy, but within this time frame, it is recommended to perform the test as early as possible.
The results of the test (depending on its effectiveness) indicate any abnormality that points to the presence of Down syndrome, and this numerical value is done using a bio-computer method, calculating a z-score. The expectant mother receives her PrenaTest® results within 8 working days.
PrenaTest® testing options:
PrenaTest® Basic (Down syndrome detection)
PrenaTest® Optimum (Down syndrome, Edwards syndrome, Patau syndrome detection)
PrenaTest® Plus (Down syndrome, Edwards syndrome, Patau syndrome, sex chromosome abnormalities detection)